Broncos Preview: Can Bo Nix Carry the Load vs. Cardinals?

Denver Broncos · 2026-10-23 · Beatline Sports Podcast Network

Christine: The defense has been carrying this team on their backs all season, but heading into Week 7 against Arizona, Bo Nix is saying it’s his turn to shoulder the load.

Christine: Welcome to the Beatline Podcast Network, I’m Christine Breen, and joining me as always is our lead analyst, Jason Kamenetzky. Jason, what a week this is turning out to be for Denver.

Jason: It really is, Christine. We’ve talked about this defensive identity for weeks, but now we have to see if the offense can actually keep pace with Arizona in a game that feels like it could go either way.

Christine: Exactly. So here is your roadmap for today’s preview of the Denver Broncos at the Arizona Cardinals. First, we’re breaking down the biggest storylines leading into Sunday night football. Then, we’ll look at the key players and that critical injury report. And finally, we’ll give you our keys to the game and a bold prediction.

Jason: We are coming off a gritty 17-14 win over Seattle, so let’s dive right into how this team sets up for the Cardinals.

Christine: Let’s start with the elephant in the room. The headlines are screaming that Bo Nix wants to carry the offense. But looking back at that Seattle game, he went 17 for 27 for just 107 yards. Is that enough firepower for Sunday?

Jason: That’s the tension, isn’t it? On paper, 107 yards is not a lot. But context matters. The Broncos’ defense was holding strong, they were winning the turnover battle, and the running game was moving the chains. J.K. Dobbins had 41 yards on 17 carries, which is efficiency, not volume.

Christine: Right, and RJ Harvey added a touchdown run. So the ground game worked. But against Arizona, can they rely on that same script? The Cardinals aren't Seattle.

Jason: They absolutely are not. And that brings us to the first major storyline: Jonathon Cooper’s return. Jeff Legwold wrote about how Cooper’s presence creates more one-on-one opportunities for Nik Bonitto. If Cooper is back on the edge, Bonitto gets double-teamed less, which means more pressure on the quarterback.

Christine: That is huge. Because if the pass rush is better, Bo Nix has more time to find his receivers. But we know the secondary is banged up. Pat Surtain II is questionable, and Talanoa Hufanga is doubtful. That changes the entire coverage scheme for Arizona’s passing attack.

Jason: It does. When you lose Hufanga, you lose that safety help over the top. You’re forced to play more man coverage or bring safeties up into the box, which leaves seams open. If Surtain plays, he’s still a shutdown corner, but playing with limitations is different than playing at 100 percent.

Christine: So, the story is this: Can the Broncos' elite defense hold up despite the injuries, while Bo Nix finds his rhythm in the passing game? It’s a delicate balance.

Christine: Before we get into the injury details and our predictions, we need to talk about something important. This show is free, with no ads and no paywall, because of supporters like you. Your contributions protect that independence and keep us daily. Please consider chipping in via the link in the episode description.

Jason: Thanks, Christine. Let’s get into the nitty-gritty of the roster. Who are the guys we need to watch on both sides of the ball?

Christine: Well, starting with the offense, we have to talk about Evan Engram. He’s been a reliable target for Nix, but also Alex Singleton. Singleton had 13 tackles in the Seattle game. That is an insane workload for a linebacker.

Jason: Singleton is the heart of this defense. But here’s the tactical issue: if Arizona decides to attack the middle of the field, Singleton has to be everywhere. With Hufanga doubtful, the safety net is gone. If Arizona’s tight ends or slot receivers find space between the hashes, Singleton might not be able to cover it all by himself.

Christine: That’s scary. And on the other side, we have to mention the receiving corps. Courtland Sutton is the big weapon, but Jaylen Waddle is questionable. If Waddle can’t go, who steps up? Lil’Jordan Humphrey? Marvin Mims Jr.?

Jason: If Waddle is out, you have to look at Troy Franklin. He’s young, but he’s fast. Against Arizona, if the Broncos want to stretch the field vertically, Franklin is the guy to exploit single coverage. But if the line doesn’t protect, speed doesn’t matter. And that goes back to Nik Bonitto.

Christine: Let’s circle back to the injury report for a second because it’s getting crowded. Tyler Badie is questionable. Jonah Coleman is on IR. Elijah Arroyo is on IR. And we already knew about Surtain and Hufanga.

Jason: It’s a lot of pieces missing. But remember, this is a 4-2 team. They’re second in the AFC West. They’ve found ways to win without everyone healthy. The question is whether they can maintain that grit against an Arizona team that is hungry to prove itself.

Christine: And don’t forget Sam Ehlinger. If Nix struggles, does the coaching staff turn to Ehlinger? Or do they stick with Nix to build chemistry?

Jason: I doubt they pull Nix yet. The plan is to get him comfortable. But if the offensive line gets pushed around, you might see more play-action or quick slants to use Ehlinger’s mobility if he enters the game. But my bet is Nix starts.

Christine: Okay, so we have the defensive injuries, the potential loss of Waddle, and the boost from Cooper returning. Let’s move to our final segment: Keys to the Game and our Bold Prediction.

Jason: Here is the first key: Time of possession. In the Seattle game, the Broncos controlled the clock. J.K. Dobbins didn’t have huge yardage, but he had 17 carries. That keeps the defense fresh and gives Nix more time to make decisions.

Christine: Agreed. And the second key? Protecting the football. Sam Darnold threw two interceptions in the last game. If Arizona forces even one more turnover, the Broncos’ margin for error shrinks to zero.

Jason: Third key: Exploit the edges. With Hufanga doubtful, Arizona might try to run more deep routes. If Kris Abrams-Draine and Jahdae Barron can stay in front of their receivers, Denver wins. If not, it’s going to be a shootout.

Christine: Alright, Jason, hit me with the bold prediction. Remember, in previous episodes, we projected a narrow win around 24-20, and said Nix would throw for over 200 yards. Are we sticking with that?

Jason: I am sticking with the narrow win. The defense will keep them in it. But I’m bumping the passing yards prediction. I think Nix throws for 225 yards. Why? Because Arizona will force him to pass more if the run game is stuffed.

Christine: And I agree with the score. 24-20 feels right. It’s a grind. It’s physical. But the Broncos’ special teams gave them a boost with Wil Lutz’s 53-yarder against Seattle. That kind of reliability matters in close games.

Jason: Plus, Nik Bonitto getting a sack or two against the Cardinals’ interior line could be the difference-maker. One big play changes the whole game.

Christine: There you have it. A defensive battle where Bo Nix steps up, the Broncos hold off Arizona 24-20, and they stay atop the AFC West race.

Jason: Big game this weekend. Make sure you tune in for the full broadcast coverage.

Christine: If you enjoyed this preview, please subscribe, rate, and review the Beatline Podcast Network wherever you listen. It helps more fans find us.

Jason: Stay locked in. Stay loud. Go Broncos.